Last Updated on July 29, 2021 by Debra Rose Wilson, PhD, MSN, RN, IBCLC, AHN-BC, CHT
How do you get Herpes/How can you get it? HSV Causes:
Herpes is caused by the herpes simplex virus type 1 (HSV1) or herpes simplex virus type 2 (HSV2). Genital herpes can be caused by either virus, while oral herpes is more commonly caused by HSV1.
It is spread by contact with the mouth, genitals, or skin with either developed or developing herpes blisters. Transmission is also possible between outbreaks, when visible or asymptomatic viral shedding occurs from the original site of infection.
Both HSV1 and HSV2 are most often spread by people who are asymptomatic and not experiencing any noticeable signs or symptoms.
How to tell if you have HSV? Symptoms:
Most people with HSV are unaware they have it and have no noticeable signs or symptoms.
For those with outbreaks during the initial episode, there may be:
- Pain at the site of the sore(s)
- Painful urination
- Vaginal discharge
- Swollen glands
- Fever
- Body aches
- Rash
Typically, another episode can appear weeks or months after the first, but it is almost always less severe and shorter in duration. In 20% of genital herpes infections, when signs do occur, they typically appear as one or more blisters on or around the genitals or rectum.
- Fever
- Tingling at the sight of outbreak
- Itching
- Pain, burning, or pressure at the site of original infection
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How to know if you have HSV? Herpes Tests:
If blisters are present, a health-care provider can diagnose HSV1 & HSV2 by sight, but clinical diagnosis should be confirmed by a laboratory blood test.
Relief spells (Rolaids?!) HSV Treatment:
There is no treatment for HSV and the infection can stay in the body for life.
However, there are anti-viral medications to treat outbreaks and to lessen the frequency of HSV occurrences. People experiencing frequent outbreaks can be prescribed an anti-viral medication to take daily – this is called suppressive therapy and can reduce frequency and duration of outbreaks.
Some people recommend taking a supplement of the amino-acid lysine (L-lysine). While some research has suggested that lysine supplements can reduce the frequency of recurrences or reduce healing time, other studies have been inconclusive.
What’s going to happen to me?!!?! Herpes Expectations:
Genital herpes can cause recurrent painful genital sores, and infection can be especially severe in people with suppressed immune systems. Regardless of severity of symptoms, genital HSV frequently causes psychological distress in people who know they have it.
Things to be aware of… HSV Complications:
HSV infections can increase the risk for HIV infections two-fold. The immune response to HSV2 can also make someone who has HIV more infectious.
Pregnant people who have an active genital herpes infection when they give birth may pass the infection to their baby.
- The risk of passing the infection to the baby is highest if the person first becomes infected during pregnancy. The risk for severe infection in the baby is much lower in recurrent outbreaks.
- Babies of people who become infected during pregnancy are at risk for premature birth. The baby may develop brain infection (meningitis, encephalitis), chronic skin infection, severe developmental delays, or death.
- People with a history of genital HSV who have occasional or no outbreaks rarely spread the infection to their babies.
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References
- Symptoms
- Armangue, Thaís, et al. “Frequency, symptoms, risk factors, and outcomes of autoimmune encephalitis after herpes simplex encephalitis: a prospective observational study and retrospective analysis.” The Lancet Neurology 17.9 (2018): 760-772.
- Groves, Mary Jo. “Genital herpes: a review.” Am Fam Physician 93.11 (2016): 928-934.
- Jonker, Iris, et al. “The association between herpes virus infections and functional somatic symptoms in a general population of adolescents. The TRAILS study.” PloS one 12.10 (2017): e0185608.
- Verhoeven, Dirk HJ, et al. “Reactivation of human herpes virus-6 after pediatric stem cell transplantation: risk factors, onset, clinical symptoms and association with severity of acute graft-versus-host disease.” The Pediatric infectious disease journal 34.10 (2015): 1118-1127.
- Croll, Benjamin J., et al. “MRI diagnosis of herpes simplex encephalitis in an elderly man with nonspecific symptoms.” Radiology case reports 12.1 (2017): 159-160.
- Testing
- Tan, S. K., and B. A. Pinsky. “Molecular Testing for Herpes Viruses.” Diagnostic Molecular Pathology. Academic Press, 2017. 89-101.
- Piret, Jocelyne, Nathalie Goyette, and Guy Boivin. “Novel method based on real-time cell analysis for drug susceptibility testing of herpes simplex virus and human cytomegalovirus.” Journal of clinical microbiology 54.8 (2016): 2120-2127.
- Hauser, Ronald G., et al. “Reply to Galen,“Screening cerebrospinal fluid prior to herpes simplex virus pcr testing might miss cases of herpes simplex encephalitis”.” Journal of clinical microbiology 55.10 (2017): 3144.
- Hauser, Ronald G., et al. “Cost-effectiveness study of criteria for screening cerebrospinal fluid to determine the need for herpes simplex virus PCR testing.” Journal of clinical microbiology 55.5 (2017): 1566-1575.
- Bohn-Wippert, Kathrin, et al. “Resistance testing of clinical herpes simplex virus type 2 isolates collected over 4 decades.” International Journal of Medical Microbiology 305.7 (2015): 644-651.
- Treatment
- Wilhelmus, Kirk R. “Antiviral treatment and other therapeutic interventions for herpes simplex virus epithelial keratitis.” Cochrane Database of Systematic Reviews 1 (2015).
- James, Scott H., and David W. Kimberlin. “Neonatal herpes simplex virus infection: epidemiology and treatment.” Clinics in perinatology 42.1 (2015): 47-59.
- Jeon, Young Hoon. “Herpes zoster and postherpetic neuralgia: practical consideration for prevention and treatment.” The Korean journal of pain 28.3 (2015): 177.
- Eppink ST, Kumar S, Miele K, Chesson H. Lifetime medical costs of genital herpes in the United States: Estimates from insurance claims. Sex Transm Dis. (2021).
- Breier, Alan, et al. “Herpes simplex virus 1 infection and valacyclovir treatment in schizophrenia: Results from the VISTA study.” Schizophrenia research (2018).
- Varanasi, Siva Karthik, et al. “Azacytidine treatment inhibits the progression of herpes stromal keratitis by enhancing regulatory T cell function.” Journal of virology 91.7 (2017): e02367-16.
- Prevention
- Abdool Karim, Salim S., et al. “Tenofovir gel for the prevention of herpes simplex virus type 2 infection.” New England Journal of Medicine 373.6 (2015): 530-539.
- Jeon, Young Hoon. “Herpes zoster and postherpetic neuralgia: practical consideration for prevention and treatment.” The Korean journal of pain 28.3 (2015): 177.
- Marrazzo, Jeanne M., et al. “Tenofovir Gel for Prevention of Herpes Simplex Virus Type 2 Acquisition: Findings From the VOICE Trial.” The Journal of infectious diseases (2019).
- Chi, Ching‐Chi, et al. “Interventions for prevention of herpes simplex labialis (cold sores on the lips).” Cochrane Database of Systematic Reviews 8 (2015).
- Colombel, Jean-Frédéric. “Herpes zoster in patients receiving JAK inhibitors for ulcerative colitis: mechanism, epidemiology, management, and prevention.” Inflammatory bowel diseases 24.10 (2018): 2173-2182.
- Transmission
- Oevermann, Lena, et al. “Transmission of chromosomally integrated human herpes virus-6A via haploidentical stem cell transplantation poses a risk for virus reactivation and associated complications.” Bone marrow transplantation (2019): 1.
- Tronstein E, Johnston C, Huang ML, Selke S, Magaret A, Warren T, Corey L, Wald A. Genital shedding of herpes simplex virus among symptomatic and asymptomatic persons with HSV-2 infection. JAMA. (2011).
- Pandey, Utsav, et al. “Inferred father-to-son transmission of herpes simplex virus results in near-perfect preservation of viral genome identity and in vivo phenotypes.” Scientific reports 7.1 (2017): 13666.
- Ramchandani M, Selke S, Magaret A, Barnum G, Huang MW, Corey L, Wald A. Prospective cohort study showing persistent HSV-2 shedding in women with genital herpes 2 years after acquisition. Sex Transm Infect. (2018).
- Ceña-Diez, Rafael, et al. “Prevention of vaginal and rectal herpes simplex virus type 2 transmission in mice: Mechanism of antiviral action.” International journal of nanomedicine 11 (2016): 2147.
- Omori, Ryosuke, and Laith J. Abu-Raddad. “Sexual network drivers of HIV and herpes simplex virus type 2 transmission.” AIDS (London, England) 31.12 (2017): 1721.
- Aebi-Popp, Karoline, et al. “High prevalence of herpes simplex virus (HSV)-type 2 co-infection among HIV-positive women in Ukraine, but no increased HIV mother-to-child transmission risk.” BMC pregnancy and childbirth 16.1 (2016): 94.
Amie
I found this really great video about herpes type 1 and 2 here
Jenelle Marie
Hi Amie –
I had to remove your video, only because it was an advertisement for Herpeset….while I’ve heard it’s useful to some, there’s quite a bit of controversy around its use and effectiveness, and I’d hate to send the wrong message about the product to my readers. The video did, however, have some great statistics, albeit, some of the pictures were fuzzy and hard to see.
In replace of your herpes video, I think this one is excellent and it is not advertising for a specific product: https://youtu.be/NbEGIidxqqQ
In either case, thank you for your comment and I applaud your efforts to seek out information – youtube has some great informational videos out there – some not so great…. I have a playlist established for STD Videos which are informative, if you’d like to check them out here: https://www.youtube.com/user/thestdproject/videos?view=1
Thanks again!
John
I think it would be useful to have more information around options (if any) for someone with herpes to continue to have safe sex. Is there any risk with having sex using a condom with a herpes carrier that does not currently have an outbreak?
I gather that is spread through contact so if the groin area (not covered by the condom) comes into contact then is there still risk there?
Jenelle Marie
Hi John –
Thanks so much for your suggestion. We write about safer sex with herpes, but it’s as a forum post and not a traditional blog entry; so, you’re right – we should place the information in a couple of different locations for our readers. I’ve put it down on our to-do list, as I think there are probably others looking for the same thing and unable to find it via the forum!
To answer your question, though, yes, genital herpes is spread through skin-to-skin contact; so, there is still a risk when using barriers (condoms) as well; albeit, the risk is reduced when using protection.
Thanks again for a great suggestion!