Last Updated on July 29, 2021 by Stacy Sampson, DO
These briefs are intended to give readers (specifically those who weren’t aware many of these STIs/STDs existed) an overview of each STI/STD, their commonality, treatment options, and diagnostic tests available.
This information is by no means all-encompassing and The STI Project encourages using these briefs as primers and then further delving into the resources section when subsequent questions arise.
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Lymphogranuloma Venereum Symptoms, Test & Treatment
Common? Thought to be rare – however, its identification is not always obvious, so the number of cases of LGV in the United States is uncertain – Around 500 people contract it in the U.S. annually (known cases)
Symptoms Genital papule(s) (e.g., raised surface or bumps) and or ulcers, and swelling of the lymph glands in the genital area. LGV may also produce rectal ulcers, bleeding, pain, and discharge, especially among those who practice receptive anal intercourse.
Cure? Three weeks of antibiotics
Bacterial/Viral/ Fungal/Parasitic Bacterial
Test A health care provider can collect a specimen and send the sample to their state health department for referral to CDC
Life-Long? No
Life-Threatening? No – however, LGV may facilitate transmission and acquisition of HIV
- Think You Might Have an STI/STD?
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- Detailed LGV Symptoms
- Pictures of LGV
- Looking for more information about lymphogranuloma venereum (LGV)?
- Looking for STI testing centers, lymphogranuloma venereum (LGV) treatment, STI hotlines, or STI blogs and forums?
- Would you like to read stories about people living with an STI/STD?
References
- Symptoms
- Charest, Louise, Judith Fafard, and Zoë R. Greenwald. “Asymptomatic urethral lymphogranuloma venereum: a case report.” International journal of STD & AIDS 29.8 (2018): 828-830.
- Diaz, Asuncion, Marta Ruiz-Algueró, and Victoria Hernando. “Lymphogranuloma venereum in Spain, 2005–2015: A literature review.” Medicina Clínica (English Edition) (2018).
- O’Byrne, Patrick, et al. “Approach to lymphogranuloma venereum.” Canadian Family Physician 62.7 (2016): 554-558.
- Belda, Walter. “Sexually transmitted diseases.” Dermatology in Public Health Environments. Springer, Cham, 2018. 139-156.
- Sullivan, Brian, et al. “Lymphogranuloma venereum (LGV) proctocolitis mimicking rectal lymphoma.” Radiology case reports 13.6 (2018): 1119-1122.
- Testing
- Maxwell, Alexandra Z., Penelope R. Cliff, and John A. White. “O12 LGV testing: are we identifying all cases in a timely manner?.” Sex Transm Infect 93.Suppl 1 (2017): A4-A5.
- Were, John, et al. “P219 Responding to the LGV epidemic: are the right patients being tested for LGV?.” (2016): A93-A93.
- Maxwell, Alexandra, Penelope Cliff, and John White. “O12 LGV testing.” Sexually Transmitted Infections 93.Suppl_1 (2017).
- Griffiths, Tristan, and Nneka Nwokolo. “O002 Rates of asymptomatic lymphogranuloma venereum (LGV) in men who have sex with men (MSM).” (2016): A1-A1.
- Herrmann, Björn, et al. “P3. 27 Lymphogranuloma venereum in sweden 2004–2016: increased rates among hiv-negative men who have sex with men and changed genotypes.” (2017): A103-A103.
- Treatment
- Simons, Rebecca, et al. “Observed treatment responses to short-course doxycycline therapy for rectal lymphogranuloma venereum in men who have sex with men.” Sexually transmitted diseases 45.6 (2018): 406-408.
- Stoner, Bradley P., and Stephanie E. Cohen. “Lymphogranuloma venereum 2015: clinical presentation, diagnosis, and treatment.” Clinical Infectious Diseases 61.suppl_8 (2015): S865-S873.
- Fauzi, Mohd, Sameena Ahmad, and Cara Saxon. “P135 A review of local test of cure (TOC) practice following treatment for rectal chlamydia and lymphogranuloma venereum.” Sex Transm Infect 93.Suppl 1 (2017): A61-A61.
- Leeyaphan, Charussri, et al. “Treatment outcomes for rectal lymphogranuloma venereum in men who have sex with men using doxycycline, azithromycin, or both: a review of clinical cases.” Sexually transmitted diseases 44.4 (2017): 245-248.
- Donachie, Alastair, et al. “Lymphogranuloma venereum (LGV) in men who have sex with men (MSM): a re-emerging problem, Malta, 2018.” Eurosurveillance 23.43 (2018).
- Prevention
- Reyes-Urueña, J. M., et al. “Lymphogranuloma venereum in Barcelona, 2007–2012: the role of seroadaptation in men who have sex with men.” Epidemiology & Infection 143.1 (2015): 184-188.
- Caumes, Eric. “Letter to the editor: Prevention of bacterial sexually transmitted infections (STI) in France: why not recommend using condoms and safer sex?.” Eurosurveillance 24.12 (2019): 1900171.
- Donachie, Alastair, et al. “Lymphogranuloma venereum (LGV) in men who have sex with men (MSM): a re-emerging problem, Malta, 2018.” Eurosurveillance 23.43 (2018).
- Brook, Gary, et al. “2017 European guideline for the screening, prevention and initial management of hepatitis B and C infections in sexual health settings.” International journal of STD & AIDS 29.10 (2018): 949-967.
- Mungati, M., et al. “P09. 23 High prevalence of hiv infection among patients with sti syndromes in zimbabwe: implications for prevention.” (2015): A156-A157.
- Transmission
- de Vries, Henry John C. “The Enigma of Lymphogranuloma Venereum Spread in Men Who Have Sex With Men: Does Ano-Oral Transmission Plays a Role?.” (2016): 420-422.
- Boutin, C. A., et al. “LGV in Quebec.” CCDR 44 (2018): 2.
- Templeton, David J., et al. “Enhanced surveillance of a lymphogranuloma venereum outbreak in Sydney 2010–2012.” Australian and New Zealand journal of public health 40.4 (2016): 368-370.
- de Vries, Henry JC. “Lymphoganuloma venereum in the Western world, 15 years after its re-emergence: new perspectives and research priorities.” Current opinion in infectious diseases 32.1 (2019): 43-50.
- Touati, Arabella, et al. “Did L Strains Responsible for Lymphogranuloma Venereum Proctitis Spread Among People With Genital Chlamydia trachomatis Infection in France in 2013?.” Sexually transmitted diseases 43.6 (2016): 374-376.
