Last Updated on July 29, 2021 by Stacy Sampson, DO
Mycoplasma Genitalium STI/STD Brief
These briefs are intended to give readers (specifically those who weren’t aware many of these STIs/STDs existed) an overview of each STI/STD, their commonality, treatment options, and diagnostic tests available.
This information is by no means all-encompassing and The STI Project encourages using these briefs as primers and then further delving into the resources section when subsequent questions arise.
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Mycoplasma Genitalium Symptoms, Test & Treatment
Common? Quite common – There is evidence to suggest that in the United States, mycoplasma has become one of the most common STI diagnosed in young people. Around 2 million people contract it in the U.S. annually
Symptoms Usually none! Sometimes vaginal itching, a burning or otherwise painful sensation when urinating, pain during sex, discharge of the urethra
Cure? Treated with antibiotics
Bacterial/Viral/ Fungal/Parasitic Bacterial
Test Testing your urine and taking swabs from your vagina or penis
Life-Long? No
Life-Threatening? No, but doctors think the long-term consequences of a mycoplasma infection may be similar to those of more well-known STIs/STDs such as gonorrhea and chlamydia.
- How to Not Give an Eff about Having an STI
- Detailed Mycoplasma Genitalium Symptoms
- About STIs/STDs – Your Ultimate Reference Guide
- Mycoplasma Genitalium In-Depth
- Looking for more information about mycoplasma genitalium?
- Looking for STI testing centers, mycoplasma genitalium treatment, STI hotlines, or STI blogs and forums?
- Would you like to read stories about people living with an STI/STD?
References
- Symptoms
- Lis, Rebecca, Ali Rowhani-Rahbar, and Lisa E. Manhart. “Mycoplasma genitalium infection and female reproductive tract disease: a meta-analysis.” Clinical Infectious Diseases 61.3 (2015): 418-426.
- Horner, Patrick J., and David H. Martin. “Mycoplasma genitalium infection in men.” The Journal of infectious diseases 216.suppl_2 (2017): S396-S405.
- Slifirski, Josephine B., et al. “Mycoplasma genitalium infection in adults reporting sexual contact with infected partners, Australia, 2008–2016.” Emerging infectious diseases 23.11 (2017): 1826.
- Ona, Samsiya, Rose L. Molina, and Khady Diouf. “Mycoplasma genitalium: an overlooked sexually transmitted pathogen in women?.” Infectious diseases in obstetrics and gynecology 2016 (2016).
- Ison, Catherine A., et al. “Highlighting the clinical need for diagnosing Mycoplasma genitalium infection.” International journal of STD & AIDS 29.7 (2018): 680-686.
- Testing
- Björnelius, Eva, Charlotta Magnusson, and Jørgen Skov Jensen. “Mycoplasma genitalium macrolide resistance in Stockholm, Sweden.” Sex Transm Infect 93.3 (2017): 167-168.
- Unemo, Magnus, and Jorgen S. Jensen. “Antimicrobial-resistant sexually transmitted infections: gonorrhoea and Mycoplasma genitalium.” Nature Reviews Urology 14.3 (2017): 139.
- Jensen, Jørgen Skov, and Catriona Bradshaw. “Management of Mycoplasma genitalium infections–can we hit a moving target?.” BMC infectious diseases 15.1 (2015): 343.
- Romano, Sarah S., et al. “Long Duration of Asymptomatic Mycoplasma genitalium Infection After Syndromic Treatment for Nongonococcal Urethritis.” Clinical Infectious Diseases (2018).
- Getman, Damon, et al. “Mycoplasma genitalium prevalence, coinfection, and macrolide antibiotic resistance frequency in a multicenter clinical study cohort in the United States.” Journal of clinical microbiology 54.9 (2016): 2278-2283.
- Treatment
- Bradshaw, Catriona S., Jorgen S. Jensen, and Ken B. Waites. “New horizons in Mycoplasma genitalium treatment.” The Journal of infectious diseases 216.suppl_2 (2017): S412-S419.
- Read, Tim RH, et al. “Outcomes of resistance-guided sequential treatment of Mycoplasma genitalium infections: a prospective evaluation.” Clinical Infectious Diseases 68.4 (2018): 554-560.
- Gesink, Dionne, et al. “Mycoplasma genitalium in Toronto, Ont: estimates of prevalence and macrolide resistance.” Canadian Family Physician 62.2 (2016): e96-e101.
- Gaydos, Charlotte A. “Mycoplasma genitalium: accurate diagnosis is necessary for adequate treatment.” The Journal of infectious diseases 216.suppl_2 (2017): S406-S411.
- Guschin, Alexander, et al. “Treatment efficacy, treatment failures and selection of macrolide resistance in patients with high load of Mycoplasma genitalium during treatment of male urethritis with josamycin.” BMC infectious diseases 15.1 (2015): 40.
- Prevention
- Golden, Matthew R., Kimberly A. Workowski, and Gail Bolan. “Developing a public health response to Mycoplasma genitalium.” The Journal of infectious diseases 216.suppl_2 (2017): S420-S426.
- Balkus, J. E., et al. “3: Detection of macrolide resistance-mediating mutations among women with mycoplasma genitalium infection in the preventing vaginal infections trial.” American Journal of Obstetrics & Gynecology 215.6 (2016): S828.
- Workowski, Kimberly A. “Centers for Disease Control and Prevention sexually transmitted diseases treatment guidelines.” Clinical Infectious Diseases 61.suppl_8 (2015): S759-S762.
- Read, Tim RH, et al. “Use of pristinamycin for macrolide-resistant Mycoplasma genitalium infection.” Emerging infectious diseases 24.2 (2018): 328.
- Dirks, J. A. M. C., et al. “P3. 100 High mycoplasma genitalium prevalence in chlamydia trachomatis positive patients.” (2017): A130-A130.
- Transmission
- Unemo, Magnus, and Jorgen S. Jensen. “Antimicrobial-resistant sexually transmitted infections: gonorrhoea and Mycoplasma genitalium.” Nature Reviews Urology 14.3 (2017): 139.
- Jensen, Jørgen Skov, et al. “2016 European guideline on Mycoplasma genitalium infections.” Journal of the European Academy of Dermatology and Venereology 30.10 (2016): 1650-1656.
- Lillis, Rebecca A., David H. Martin, and M. Jacques Nsuami. “Mycoplasma genitalium Infections in Women Attending a Sexually Transmitted Disease Clinic in New Orleans.” Clinical Infectious Diseases (2018).
- Pereyre, Sabine, et al. “Mycoplasma genitalium and Trichomonas vaginalis in France: a point prevalence study in people screened for sexually transmitted diseases.” Clinical Microbiology and Infection 23.2 (2017): 122-e1.
- Edouard, Sophie, et al. “Mycoplasma genitalium, an agent of reemerging sexually transmitted infections.” Apmis 125.10 (2017): 916-920.
