Last Updated on July 29, 2021 by Stacy Sampson, DO
Nongonococcal Urethritis STI/STD Brief
These briefs are intended to give readers (specifically those who weren’t aware many of these STIs/STDs existed) an overview of each STI/STD, their commonality, treatment options, and diagnostic tests available.
This information is by no means all-encompassing and The STI Project encourages using these briefs as primers and then further delving into the resources section when subsequent questions arise.
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Nongonococcal Urethritis Symptoms, Test & Treatment
Common? Very common – Around 3 million people contract it in the U.S. annually – rarely affects people with vulvas/vaginas
Symptoms Often no obvious symptoms occur – when symptoms do occur they may include genital discharge, pain or burning while urinating, itching, or genital soreness. NGU of the throat can cause a sore throat.
Cure? Treated with antibiotics
Bacterial/Viral/ Fungal/Parasitic Bacterial
Test A medical practitioner can diagnose through visible urethral inflammation (swelling), urethral swab or oral swab, or via a pap smear
Life-Long? No
Life-Threatening? No, but left untreated nongonococcal urethritis (NGU) can cause epididymitis or pelvic inflammatory disease – both of which can lead to infertility.
- Detailed NGU Symptoms
- Nongonococcal Urethritis In-Depth
- Looking for more information about nongonococcal urethritis (NGU)?
- How to Not Give an Eff about Having an STI
- Looking for STD testing centers, nongonococcal urethritis treatment, STD hotlines, or STD blogs and forums?
- Would you like to read stories about people living with an STI/STD?
References
- Symptoms
- Frølund, Maria, et al. “Urethritis-associated pathogens in urine from men with non-gonococcal urethritis: a case-control study.” Acta dermato-venereologica 96.5 (2016): 689-695.
- Read, Tim RH, et al. “Symptoms, Sites, and Significance of Mycoplasma genitalium in Men Who Have Sex with Men.” Emerging infectious diseases 25.4 (2019): 719-727.
- Ng, Andrea, and Jonathan DC Ross. “Trichomonas vaginalis infection: How significant is it in men presenting with recurrent or persistent symptoms of urethritis?.” International journal of STD & AIDS 27.1 (2016): 63-65.
- Jordan, Stephen J., et al. “Defining the Urethritis Syndrome in Men Using Patient Reported Symptoms.” Sexually transmitted diseases 45.7 (2018): e40-e42.
- Horie, Kengo, et al. “‘Haemophilus quentini’in the urethra of men complaining of urethritis symptoms.” Journal of Infection and Chemotherapy 24.1 (2018): 71-74.
- Testing
- Horner, P., et al. “Should we be testing for urogenital Mycoplasma hominis.” (2018).
- Abbott, Collette E., et al. “A case of rectal ureaplasma infection and implications for testing in young men who have sex with men: the P18 cohort study.” LGBT health 4.2 (2017): 161-163.
- Trembizki, Ella, et al. “Opportunities and pitfalls of molecular testing for detecting sexually transmitted pathogens.” Pathology 47.3 (2015): 219-226.
- Davies, Nicola. “Mycoplasma genitalium: the need for testing and emerging diagnostic options.” MLO Med Lab Obs 47.12 (2015): 8.
- Zhang, Zhanguo, et al. “NGU: Development of a two‐bed circulating fluidized bed reactor system for nonoxidative aromatization of methane over Mo/HZSM‐5 catalyst.” Environmental Progress & Sustainable Energy 35.2 (2016): 325-333.
- Treatment
- Bachmann, Laura H., et al. “Advances in the understanding and treatment of male urethritis.” Clinical Infectious Diseases 61.suppl_8 (2015): S763-S769.
- Couldwell, Deborah L., and David A. Lewis. “Mycoplasma genitalium infection: current treatment options, therapeutic failure, and resistance-associated mutations.” Infection and drug resistance 8 (2015): 147.
- Romano, Sarah S., et al. “Long Duration of Asymptomatic Mycoplasma genitalium Infection After Syndromic Treatment for Nongonococcal Urethritis.” Clinical Infectious Diseases (2018).
- Kissinger, Patricia, et al. “Azithromycin treatment failure for Chlamydia trachomatis among heterosexual men with nongonococcal urethritis.” Sexually transmitted diseases 43.10 (2016): 599.
- Tabrizi, Sepehr N. “Mycoplasma genitalium: update on diagnosis, treatment and resistance.” Pathology 47 (2015): S50.
- Prevention
- Workowski, Kimberly A. “Centers for Disease Control and Prevention sexually transmitted diseases treatment guidelines.” Clinical Infectious Diseases 61.suppl_8 (2015): S759-S762.
- Hogben, Matthew, et al. “Partner services in STD prevention programs: a review.” Sexually transmitted diseases 43.0 0 1 (2016): S53.
- Ong, Jason J., et al. “Should female partners of men with non-gonococcal urethritis, negative for Chlamydia trachomatis and Mycoplasma genitalium, be informed and treated? Clinical outcomes from a partner study of heterosexual men with NGU.” Sexually transmitted diseases 44.2 (2017): 126-130.
- Territo, Heather, and John V. Ashurst. “Nongonococcal Urethritis (NGU).” StatPearls [Internet]. StatPearls Publishing, 2018.
- Ekiel, Alicja, et al. “Prevalence of Urogenital Mycoplasmas Among Men with NGU in Upper Silesia, Poland. Preliminary Study.” Polish journal of microbiology 65.1 (2016): 93-95.
- Transmission
- Saxena, Ajit, Reetika Dawar, and Upasana Bora. “Haemophilus parainfluenzae urethritis through orogenital transmission.” Indian journal of sexually transmitted diseases and AIDS 39.2 (2018): 127.
- Ong, Jason J., et al. “Should female partners of men with non-gonococcal urethritis, negative for Chlamydia trachomatis and Mycoplasma genitalium, be informed and treated? Clinical outcomes from a partner study of heterosexual men with NGU.” Sexually transmitted diseases 44.2 (2017): 126-130.
- Workowski, Kimberly A. “Centers for Disease Control and Prevention sexually transmitted diseases treatment guidelines.” Clinical Infectious Diseases 61.suppl_8 (2015): S759-S762.
- Hogben, Matthew, et al. “Partner services in STD prevention programs: a review.” Sexually transmitted diseases 43.0 0 1 (2016): S53.
- Read, Tim RH, et al. “Symptoms, Sites, and Significance of Mycoplasma genitalium in Men Who Have Sex with Men.” Emerging infectious diseases 25.4 (2019): 719-727.
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